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Sunday, April 26, 2020

Coronavirus: Sometimes You Find What You Look For

From the video linked below...
Would this get up really protect you from getting and/or spreading the most dangerous viruses on earth?

I am intrigued by this last blog post (https://www.nature.com/articles/nm.3985):

The emergence of severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome (MERS)-CoV underscores the threat of cross-species transmission events leading to outbreaks in humans. Here we examine the disease potential of a SARS-like virus, SHC014-CoV, which is currently circulating in Chinese horseshoe bat populations[1]. Using the SARS-CoV reverse genetics system[2], we generated and characterized a chimeric virus expressing the spike of bat coronavirus SHC014 in a mouse-adapted SARS-CoV backbone. The results indicate that group 2b viruses encoding the SHC014 spike in a wild-type backbone can efficiently use multiple orthologs of the SARS receptor human angiotensin converting enzyme II (ACE2), replicate efficiently in primary human airway cells and achieve in vitro titers equivalent to epidemic strains of SARS-CoV. Additionally, in vivo experiments demonstrate replication of the chimeric virus in mouse lung with notable pathogenesis. Evaluation of available SARS-based immune-therapeutic and prophylactic modalities revealed poor efficacy; both monoclonal antibody and vaccine approaches failed to neutralize and protect from infection with CoVs using the novel spike protein. On the basis of these findings, we synthetically re-derived an infectious full-length SHC014 recombinant virus and demonstrate robust viral replication both in vitro and in vivo. Our work suggests a potential risk of SARS-CoV re-emergence from viruses currently circulating in bat populations."

So here's a bunch of folks from the University of North Carolina and the Wuhan Virology Institute messing around with corona viruses where "... we synthetically re-derived an infectious full-length SHC014 recombinant virus and demonstrate robust viral replication both in vitro and in vivo."

So these folks are altering bat-borne corona viruses and then verifying they can replicate and transfer between living beings.

They add this SHC014 "spike" to the virus and note "... both monoclonal antibody and vaccine approaches failed to neutralize and protect from infection with CoVs using the novel spike protein."

Which appears to indicate that in a virus having this spike vaccines aren't going to do much good (which not surprisingly, WHO if you take any stock in what they say) agrees with: https://www.who.int/news-room/commentaries/detail/immunity-passports-in-the-context-of-covid-19.

So let's compare all this with the Biological Weapons Anti-Terrorism Act of 1989 (BWATA, Pub.L. 101–298, enacted May 22, 1990) which, from Wikipedia, "... was a piece of U.S. legislation that was passed into law in 1990. It provided for the implementation of the Biological Weapons Convention as well as criminal penalties for violation of its provisions."

This Act defines a biological agent as "any micro-organism, virus, infectious substance, or biological product that may be engineered as a result of biotechnology, or any naturally occurring or bioengineered component of any such microorganism, virus, infectious substance, or biological product, capable of causing death, disease, or other biological malfunction in a human, an animal, a plant, or another living organism; deterioration of food, water, equipment, supplies, or material of any kind or deleterious alteration of the environment"

Surely this work falls into this category.

Sadly, though, intent under this is hard to determine: "Whoever knowingly develops, produces, stockpiles, transfers, acquires, retains, or possesses any biological agent, toxin, or delivery system for use as a weapon, or knowingly assists a foreign state or any organization to do so, shall be fined under this title or imprisoned for life or any term of years, or both."

Clearly no one in the paper above says that this could be weaponized so it's unlikely anyone will care that they are making dangerous biological weaponry.

For the most part this site (https://www.covid-19.no/wuhan-lab-i-found-the-source-of-the-coronavirus) seems to provide a pretty good idea of the Wuhan Virology Institute did and perhaps caused as related to Covid19:


You can follow the link and watch the video.  The author speaks Chinese fluently and has a lot of history living in China so it provides a bit of a different spin on things than you usually see here.

Things I find odd here:

People knowingly going out to collect "dangerous" bat samples all over China.  As you can see from the video below they certainly may not take the types of precautions you would expect hunting something as deadly as SARS (image at top linked from here).  Exposed skin.  More cases where there doesn't seem to be much protection.  Could these folks be carriers and not even know it?


Funding for the above study comes in part from https://www.ecohealthalliance.org/partners.  Our old friend Bill Gates's foundation is linked in as "Science and Policy Adviser."  (Though the fact that vaccines would appear not to work kind of puts the Gates vaccination conspiracy model down a notch or two...)

The "missing" Chinese intern theory (upper video) makes sense and is confirmed in a Whitehouse briefing: https://www.nationalheraldindia.com/international/covid-19-virus-accidentally-leaked-by-an-intern-at-wuhan-lab-us-media.  Again, messing around with a loaded gun, so to speak.

We are we making dangerous corona-virus-based chimera and then messing with those?  Seems like an odd approach, doesn't it?  After all we don't build and detonate nuclear weapons to test our schemes to avoid them harming us.  We let loose rapid raccoons to figure out how to eradicate them.  So why do this?  Surely seems like ulterior motives mush be involved...

A lot of insight can be gained from looking at the rest of this page: (https://www.covid-19.no/wuhan-lab-i-found-the-source-of-the-coronavirus).  While this guy blames China the US, NAIH and Fauci not to mention the authors of the paper and UNC all seem to have a roll.  After all, we seem to be encouraging it.

The folks that worked on this are here: Vineet D Menachery, Boyd L Yount Jr, Kari Debbink, Sudhakar Agnihothram, Lisa E Gralinski, Jessica A Plante, Rachel L Graham, Trevor Scobey, Xing-Yi Ge, Eric F Donaldson, Scott H Randell, Antonio Lanzavecchia, Wayne A Marasco, Zhengli-Li Shi & Ralph S Baric.  Interestingly there's two people (it's pretty obvious who) from the Wuhan Institute of Virology.  You can search everyone but them.  They are a little harder to google...  Most of the rest are from UNC, Texas and other US locations.

You can also see from this page shot that folks (no one linked to this particular story in this case) cycle through the US, the labs above, Wuhan and back:


I have to agree with the "I found the source of the coronavirus" guy that people aren't real careful about the trail they leave..

What does all this mean?

I am not sure.

Certainly everyone's hands are in this: The Gates Foundation, UNC, Wuhan Institute of Virology, and a whole lot of US and Chinese players floating around between here and China.

Clearly Fauci is, at least for a while, funding all this with his $3.7 million in funding.

How much of any of this is believable given the poor rate of verifiable success incompetence in US medical studies: https://lwgat.blogspot.com/2012/05/us-scientific-medical-studies-1-in-20.html.  A sentiment echoed in this WSJ article (https://www.wsj.com/articles/the-bearer-of-good-coronavirus-news-11587746176?mod=opinion_lead_pos5) by Dr. Ioannidis (a credible source, underlines mine).

From this article: "“Several years ago, along with one of my colleagues, we had mapped 235 biases across science. And maybe the biggest cluster is biases that are trying to generate significant, spectacular, fascinating, extraordinary results,” he says. “Early results tend to be inflated. Claims for significance tend to be exaggerated.”

An example is a 2012 meta-analysis on nutritional research, in which he randomly selected 50 common cooking ingredients, such as sugar, flour and milk. Eighty percent of them had been studied for links to cancer, and 72% of the studies linked an ingredient to a higher or lower risk. Yet three-quarters of the findings were weak or statistically insignificant."

Little wonder an "accident" happened somewhere along the way...

Or was it a "deliberate" accident?

Given the general levels of ignorance in society, Chinese efforts to control the population, ridiculously biased new sources, etc. it's little wonder people are frustrated...

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